Born in Cion in Bithynia, of Christian parents Peter and Anthusa, he was baptised with the name Manuel. His parents had him taught tailoring as a trade, then his father embraced Islam and moved to Brussa. Once, when Manuel went to Brussa in the course of his work, his father found him and put great pressure on him to follow his example. Manuel refused, but in vain: the Turks circumcised him by force. Then Manuel fled to the Holy Mountain and became a monk in the skete of St Anne, receiving the name Macarius. He was a model monk for twelve years, but his soul could find no peace. "Whosoever shall deny Me before men, him will I also deny before My Father" (Matt. 10: 33) - these words of Christ"s were constantly ringing in Macarius" ears. He therefore resolved, with his elder"s blessing, to go to Brussa and openly confess his faith in Christ before the Turks, calling Mahomet a false prophet. After being flogged for a hundred and thirty days and enduring even harsher tortures, he was beheaded with the sword in Brussa on October 6th, 1590. A part of his wonderworking relics is preserved in the skete of St Anne on Mount Athos.