这位圣人出生于克里特岛。他来到君士坦丁堡看望他的亲属－斯都迪修道院院长德奥多若，并留在那里也成为一名修士。为了使自己的灵魂获得拯救，尼科拉力践修道苦行。在亚美尼亚人皇帝莱翁迫害教会期间，德奥多若和尼科拉都遭受了残酷的迫害，他们受尽了羞辱、鞭打，最后被投入到监狱中长达3年之久。圣德奥多若去世后，尼科拉成为斯都迪修道院院长。出于上帝的恩典和大能，尼科拉尚在世期间就施行了很多奇迹。尼科拉治愈了皇帝瓦西里的皇后艾弗多基雅和贵族马诺尔的妻子海伦。一个非常显赫的贵族德奥斐洛·梅里赛努斯的所有孩子都在出生后即夭折，尼科拉为他的新生女儿进行祝福，并预言说，这个女孩儿将会存活下来，并将会多生育子女。令这对父母喜悦的是，这个预言应验了。在临终当天，尼科拉召集修道院内的所有兄弟，问他们缺少什么。兄弟们说：“缺少小麦。”这位临终的圣人说：“在旷野中为以色列人提供食物的那位将会在三天之内送给你们足够的小麦。”真是这样，第三天，瓦西里皇帝所遣的一艘载满小麦的船抵达了修道院。尼科拉于公元868 年2 月4 日75 岁之际得以进入天国之家。 
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