伟大的圣人麦勒提是正教非凡的释译者和捍卫者。他的整个一生都奉献于同阿里乌异端的争斗上，阿里乌异端不承认上帝之子作为上帝，并亵渎圣三者。麦勒提曾经三次被解职并被流放到亚美尼亚。当时，正教同异端之间的争斗非常激烈，有一次，当圣麦勒提在教堂中向人们讲述有关圣三者的三位一体时，他的异端辅祭竟然走上前去用手掩盖住麦勒提的嘴。麦勒提不能用嘴讲话，只能打手势：他向上一只拳头，先伸出三个手指头，而后合起，又伸出一只手指。麦勒提参加了第二次普世大公会议（君士坦丁堡，公元381年），在那里倍受皇帝德奥多西的尊敬。在这次大公会议上，上帝通过他的这位大主教显示了一个奇迹：当麦勒提向亚流提出有关三位一体的教条时，起初，他只是伸出三只手指，一个一个地掰开，而后合为一。就在那时，从他的手指发出了一道亮光，出现在与会者的面前。在这次会议上，麦勒提确立神学家格里哥利为君士坦丁堡的牧首。早先麦勒提确立圣大瓦西里为辅祭，并为圣金口约安施浸。在大公会议结束后，麦勒提在君士坦丁堡去世，他的圣髑被转移到安提约希亚。 
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