德奥多若是圣帕科米乌斯的门徒。他出生并成长于一个异教家庭，但是在长大成人后对真正信仰有所了解，由此接受了浸礼。他听说了圣帕科米乌斯，于是悄悄地离开了父母的家，来到了帕科米乌斯所在的修道院。圣帕科米乌斯为他举行了修士剪发礼，由于德奥多若独特的热情和顺从而得到圣帕科米乌斯的赏识。当德奥多若的母亲来找他，让他回家时，他甚至都不想见到母亲，而是向上帝祷告，希望上帝能够用真理光照母亲。确实，不仅儿子没有回家，而且母亲也没有回家。这位母亲找到了附近的一座女修道院，成了一名修女，这座女修道院由圣帕科米乌斯的妹妹管理。一段时间之后，德奥多若的兄弟帕弗努提也来到了修道院，成了一名修士。不久之后，潘诺波利斯的主教召唤圣帕科米乌斯为那些打算进入修道生活的人修建一座修道院。帕科米乌斯带上了德奥多若，并将这个任务交给了他。在圣帕科米乌斯去世后，德奥多若成了圣帕科米乌斯修建的所有修道院的院长。德奥多若一生讨主喜悦指引了众多修士走向拯救之路。德奥多若得以长寿，于公元368年安息，得以进入上帝永恒的国度。 
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