麦托迪出生于西西里的斯拉库斯城。在完成世俗学科之后，斯拉库斯接受剪发礼成为修士在修道院过着禁欲生活。牧首尼基佛尔任命他为自己的助手。在圣像破坏运动期间，圣麦托迪勇敢地捍卫圣像，由此而众所周知，也正是因为如此，邪恶的德奥斐洛皇帝将他同两名普通的犯人一起流放到一个岛屿上，被关押在一个潮湿的监狱中长达七年之久，由此而变得憔悴，期间没有灯光，也没有足够的食物，如同一座坟墓一样。在虔诚的德奥多拉皇后和她的儿子弥哈伊尔在位期间，麦托迪获得了自由，并被封为牧首（根据早先圣大约尼丘斯所作的预言）。大斋期的第一个星期，麦托迪庄严地带着圣像走近教堂，并写下了圣颂典，以表示对圣像的尊重。因为无法战胜麦托迪，邪恶的异教徒雇佣了一个妇女，让她声称牧首曾经和她有不洁的关系。整个君士坦丁堡都被这个谣言给震惊了。麦托迪不知如何才能证明自己的无辜，最后，牧首克服了自己的尴尬，脱下衣服赤裸地站在法庭前，展示出自己由于斋戒而憔悴的身体。法庭相信了牧首遭受了谣言的迫害。听到这之后，人们非常高兴，羞辱了异教徒。之后，这个女人承认了自己受到逼迫，接受了金钱而制造谣言攻击牧首。这样，那些想羞辱麦托迪的人无意中使他的名声大震。这位伟大的基督的宣信者于公元846年平安离世，得以进入上帝的国度。 
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